Papautsky Lab

The Papautsky Lab conducts highly interdisciplinary research at the intersection of microfluidics, biosensing, and translational medicine. Our mission is to develop innovative microfluidic systems and point-of-care sensor technologies that advance public health, biomedical diagnostics, and environmental monitoring. We specialize in both fundamental studies and applied engineering, with a strong emphasis on microfabrication and nanofabrication techniques.

Our current research spans several key areas:

• Microfluidic platforms for personalized lung cancer models, enabling drug screening and resistance profiling using patient-derived organoids.
• Fundamental studies in inertial microfluidics, focused on label-free cell manipulation and multi-modal sorting.
• Liquid biopsy technologies, including high-throughput isolation of circulating tumor cells for non-invasive cancer diagnostics.
• Blood fractionation systems, designed for efficient separation of blood components and integration with downstream analytical tools.
• Electrochemical biosensors, previously developed for trace metal detection and biomolecule sensing in clinical and environmental samples.